Preimplantation Genetic Testing (PGT) is an advanced genetic screening technique performed during IVF to identify chromosomally healthy embryos before transfer. This significantly improves implantation rates, reduces miscarriage risk, and increases the chances of a healthy pregnancy.
PGT involves testing a few cells from an embryo at the blastocyst stage without harming its development. Only genetically normal embryos are selected for transfer, making PGT a powerful tool for couples with genetic concerns or repeated IVF failures.
Who should consider PGT?
PGT is recommended in the following clinical scenarios:
Recurrent IVF Failure
Identifies chromosomally normal embryos to improve implantation success.
Recurrent Pregnancy Loss
Reduces miscarriage risk caused by chromosomal abnormalities.
Advanced Maternal Age
Helps select genetically healthy embryos in women above 35 years.
Known Genetic Disorders
Prevents transmission of inherited genetic diseases to the baby.
Types of Preimplantation Genetic Testing
- PGT-A: Screens embryos for chromosomal abnormalities (aneuploidy)
- PGT-M: Detects specific inherited genetic disorders
- PGT-SR: Used for structural chromosomal rearrangements
Step-by-step PGT process
PGT is seamlessly integrated into the IVF cycle with precise laboratory handling.
IVF & Blastocyst Development
Embryos are cultured in the laboratory until the blastocyst stage.
Embryo Biopsy
A few cells are safely removed from the embryo for genetic testing.
Genetic Analysis
Embryos are analyzed using advanced genetic screening technology.
Frozen Embryo Transfer
Only genetically healthy embryos are selected for transfer.
Benefits & advanced genetic care
PGT significantly improves IVF outcomes by ensuring only chromosomally normal embryos are transferred. This leads to higher pregnancy rates, lower miscarriage risk, and healthier pregnancies.
Higher Implantation Rates
Selection of healthy embryos improves success per transfer.
Reduced Miscarriage Risk
Chromosomal screening prevents early pregnancy loss.
Healthy Baby Outcomes
Supports the birth of genetically healthy babies.